NK cytotoxicity mediated by CD16 but not by NKp30 is functional in Griscelli syndrome.

@article{Gazit2007NKCM,
  title={NK cytotoxicity mediated by CD16 but not by NKp30 is functional in Griscelli syndrome.},
  author={Roi Gazit and Memet Aker and Moran Elboim and Hagit Achdout and Gil Katz and Dana G. Wolf and Shulamit Katzav and Ofer Mandelboim},
  journal={Blood},
  year={2007},
  volume={109 10},
  pages={4306-12}
}
Griscelli syndrome (GS) type 2 is an autosomal recessive disorder represented by pigment dilution and impaired cytotoxic T lymphocyte (CTL) activity. NK activity has been scarcely investigated in GS patients. Here, we describe a new patient, possessing a hemophagocytic syndrome with a homozygous Q118X nonsense RAB27A mutation. Single specific primer… CONTINUE READING