NK cells modulate the inflammatory response to corneal epithelial abrasion and thereby support wound healing.

@article{Liu2012NKCM,
  title={NK cells modulate the inflammatory response to corneal epithelial abrasion and thereby support wound healing.},
  author={Qiong Liu and Clifton Smith and Wanyu Zhang and Alan R. Burns and Zhijie Li},
  journal={The American journal of pathology},
  year={2012},
  volume={181 2},
  pages={452-62}
}
Natural killer (NK) cells are lymphocytes of the innate immune system that have crucial cytotoxic and regulatory roles in adaptive immunity and inflammation. Herein, we consider a role for these cells in corneal wound healing. After a 2-mm central epithelial abrasion of the mouse cornea, a subset of classic NK cells migrated into the limbus and corneal stroma, peaking at 24 hours with an eightfold increase over baseline. Depletion of γδ T cells significantly reduced NK cell accumulation (>70… CONTINUE READING