NK cell receptors.

@article{Lanier1998NKCR,
  title={NK cell receptors.},
  author={Lewis L. Lanier},
  journal={Annual review of immunology},
  year={1998},
  volume={16},
  pages={
          359-93
        }
}
NK cells are regulated by opposing signals from receptors that activate and inhibit effector function. While positive stimulation may be initiated by an array of costimulatory receptors, specificity is provided by inhibitory signals transduced by receptors for MHC class I. Three distinct receptor families, Ly49, CD94/NKG2, and KIR, are involved in NK cell recognition of polymorphic MHC class I molecules. A common pathway of inhibitory signaling is provided by ITIM sequences in the cytoplasmic… CONTINUE READING
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