NK cell compartment in the peripheral blood and spleen in adult patients with primary immune thrombocytopenia.

@article{Ebbo2017NKCC,
  title={NK cell compartment in the peripheral blood and spleen in adult patients with primary immune thrombocytopenia.},
  author={Mikael Ebbo and Sandra Audonnet and Aur{\'e}lie Grados and Lucas Benarous and Matthieu Mah{\'e}vas and Bertrand Godeau and J. F. Viallard and Christelle Pip{\'e}roglou and C{\'e}line Cognet and Catherine Farnarier and Jean Robert Harl{\'e} and Nicolas Schleinitz and Fr{\'e}d{\'e}ric V{\'e}ly},
  journal={Clinical immunology},
  year={2017},
  volume={177},
  pages={18-28}
}
Immune thrombocytopenic purpura (ITP) is a disease characterized by antibody-mediated platelet destruction. The T- and B-cell subsets have been extensively studied in primary ITP, but the NK cell compartment has been less thoroughly explored. We investigated the NK cell receptor repertoire and the functionality of NK cells in the peripheral blood and spleen in patients with primary ITP. An immunophenotypic analysis of peripheral blood lymphocytes from patients revealed that the numbers of CD19… CONTINUE READING
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