NK-cell activity affected by some cytostatic drugs and their additives.

@article{Ujhzy1991NKcellAA,
  title={NK-cell activity affected by some cytostatic drugs and their additives.},
  author={P Ujh{\'a}zy and Ol'ga Babus{\'i}kov{\'a}},
  journal={Neoplasma},
  year={1991},
  volume={38 3},
  pages={303-12}
}
The direct effect of selected cytostatic drugs on natural killer (NK) cell activity was evaluated. Peripheral blood mononuclear cells from healthy donors were tested for their cytolytic activity in vitro in the presence of adriamycin, methotrexate, leucovorin, vincristin, cytosine arabinoside and teniposide. Most of the tested cytostatic drugs did not show to be active at concentrations comparable to their plasma level. However, diluents of some preparations (cytosine arabinoside, teniposide… CONTINUE READING