NK cell activation and protection occur independently of natural killer T cells during Trypanosoma cruzi infection.

@article{Duthie2005NKCA,
  title={NK cell activation and protection occur independently of natural killer T cells during Trypanosoma cruzi infection.},
  author={Malcolm S. Duthie and Stuart J. Kahn},
  journal={International immunology},
  year={2005},
  volume={17 5},
  pages={607-13}
}
Natural killer T (NKT) cells regulate aspects of pro-inflammatory and anti-inflammatory responses and contribute to the control of infections and chronic inflammatory diseases. During Trypanosoma cruzi infection both NKT cells and NK cells are critical to the protective response. How NKT cells interact and possibly regulate NK cells during infections remains uncertain. In vivo studies have demonstrated that specific activation of NKT cells with alpha-galactosylceramide (alpha-GalCer) leads to… CONTINUE READING