NIX induces mitochondrial autophagy in reticulocytes.

@article{Zhang2008NIXIM,
  title={NIX induces mitochondrial autophagy in reticulocytes.},
  author={J R Zhang and Paul A. Ney},
  journal={Autophagy},
  year={2008},
  volume={4 3},
  pages={354-6}
}
The controlled elimination of defective mitochondria is necessary for the health of long-lived post-mitotic cells, like cardiomyocytes and neurons. Mitochondrial elimination also occurs during the course of normal development, in lens epithelial and erythroid cells. Strikingly, at the final stage of erythroid cell maturation, newly formed erythrocytes, also known as reticulocytes, eliminate their entire cohort of mitochondria. We have employed this model to investigate the mechanism of… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 28 extracted citations

Similar Papers

Loading similar papers…