NINDS clinical trials in stroke: lessons learned and future directions.

@article{Marler2007NINDSCT,
  title={NINDS clinical trials in stroke: lessons learned and future directions.},
  author={John R. Marler},
  journal={Stroke},
  year={2007},
  volume={38 12},
  pages={
          3302-7
        }
}
Since 1977 the National Institute of Neurological Disorders and Stroke (NINDS) at the National Institutes of Health (NIH) has sponsored 28 phase 3 trials to evaluate treatments of stroke, which when all completed will have randomized a total of 44 862 patients in the United States and other countries. NINDS stroke clinical trials have been successful in finding beneficial and cost-effective treatments for cerebrovascular disease. Future trials are likely to be larger and have simpler designs… CONTINUE READING
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