NGS-Logistics: federated analysis of NGS sequence variants across multiple locations

@inproceedings{Ardeshirdavani2014NGSLogisticsFA,
  title={NGS-Logistics: federated analysis of NGS sequence variants across multiple locations},
  author={Amin Ardeshirdavani and Erika L. Souche and Luc Dehaspe and Jeroen K. J. Van Houdt and Joris Robert Vermeesch and Yves Moreau},
  booktitle={Genome Medicine},
  year={2014}
}
As many personal genomes are being sequenced, collaborative analysis of those genomes has become essential. However, analysis of personal genomic data raises important privacy and confidentiality issues. We propose a methodology for federated analysis of sequence variants from personal genomes. Specific base-pair positions and/or regions are queried for samples to which the user has access but also for the whole population. The statistics results do not breach data confidentiality but allow… CONTINUE READING