NGFR-positive desmoplastic melanomas with focal or absent S-100 staining: Further evidence supporting the use of both NGFR and S-100 as a primary immunohistochemical panel for the diagnosis of desmoplastic melanomas.

@article{Radfar2006NGFRpositiveDM,
  title={NGFR-positive desmoplastic melanomas with focal or absent S-100 staining: Further evidence supporting the use of both NGFR and S-100 as a primary immunohistochemical panel for the diagnosis of desmoplastic melanomas.},
  author={Arash Radfar and Catherine M. Stefanato and Samer H Ghosn and Jag Bhawan},
  journal={The American Journal of dermatopathology},
  year={2006},
  volume={28 2},
  pages={162-7}
}
The histologic diagnosis of desmoplastic melanoma can be challenging in circumstances in which biopsy specimens are small, or there are unsuspected clinical settings, re-excision scars, and unusual sites. This is particularly true when the overlying junctional component is absent or the spindle cells lack melanin pigment. In these instances, the importance of immunohistochemistry cannot be overemphasized. S-100 protein is the primary immunohistochemical stain used for this purpose, with a… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations

Similar Papers

Loading similar papers…