NGF Accelerates Cutaneous Wound Healing by Promoting the Migration of Dermal Fibroblasts via the PI3K/Akt-Rac1-JNK and ERK Pathways

@inproceedings{Chen2014NGFAC,
  title={NGF Accelerates Cutaneous Wound Healing by Promoting the Migration of Dermal Fibroblasts via the PI3K/Akt-Rac1-JNK and ERK Pathways},
  author={Ji-Cai Chen and Bei-Bei Lin and Hou-Wen Hu and Cai Lin and Wen-Yang Jin and Fa-biao Zhang and Yan-An Zhu and Cai-jiao Lu and Xiao-Jie Wei and Rui-jie Chen},
  booktitle={BioMed research international},
  year={2014}
}
As a well-known neurotrophic factor, nerve growth factor (NGF) has also been extensively recognized for its acceleration of healing in cutaneous wounds in both animal models and randomized clinical trials. However, the underlying mechanisms accounting for the therapeutic effect of NGF on skin wounds are not fully understood. NGF treatment significantly… CONTINUE READING