NGAL and NGALR are frequently overexpressed in human gliomas and are associated with clinical prognosis

@article{Liu2010NGALAN,
  title={NGAL and NGALR are frequently overexpressed in human gliomas and are associated with clinical prognosis},
  author={Ming-fa Liu and Tao Jin and J Shen and Zhong-ying Shen and Zhi-chao Zheng and Zeng-Liang Zhang and Li-Yan Xu and E. Herbert Li and Hai-Xiong Xu},
  journal={Journal of Neuro-Oncology},
  year={2010},
  volume={104},
  pages={119-127}
}
Recently, neutrophil gelatinase-associated lipocalin (NGAL) and its cell surface receptor, NGALR, have been shown to have critical roles in the biology of various tumors. Therefore, we investigated the expression of NGAL and NGALR in tumor sections obtained from patients with gliomas, and compared these results with the clinical characteristics of the patients. Using immunohistochemical assays, the expression levels of NGAL and NGALR were found to be up-regulated in tumor tissues, and to be… CONTINUE READING

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