NG peptides: a novel family of neurophysin-associated neuropeptides.

  title={NG peptides: a novel family of neurophysin-associated neuropeptides.},
  author={Maurice R Elphick},
  volume={458 1-2},
Neurophysins are prohormone-derived polypeptides that are required for biosynthesis of the neurohypophyseal hormones vasopressin and oxytocin. Accordingly, mutations in the neurophysin domain of the human vasopressin gene can cause diabetes insipidus. The association of neurophysins with vasopressin/oxytocin-type peptides dates back to the common ancestor of bilaterian animals and until recently it was thought to be unique. This textbook perspective on neurophysins changed with the discovery of… CONTINUE READING


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