NFI-C regulates osteoblast differentiation via control of osterix expression.

@article{Lee2014NFICRO,
  title={NFI-C regulates osteoblast differentiation via control of osterix expression.},
  author={Dong-Seol Lee and Han-Wool Choung and H Kim and Richard M. Gronostajski and Young Il Yang and Hyun-Mo Ryoo and Zang Hee Lee and Hong-Hee Kim and E S Cho and Joo-Cheol Park},
  journal={Stem cells},
  year={2014},
  volume={32 9},
  pages={2467-79}
}
In bone marrow, bone marrow stromal cells (BMSCs) have the capacity to differentiate into osteoblasts and adipocytes. Age-related osteoporosis is associated with a reciprocal decrease of osteogenesis and an increase of adipogenesis in bone marrow. In this study, we demonstrate that disruption of nuclear factor I-C (NFI-C) impairs osteoblast differentiation… CONTINUE READING