NFE2L3 (NRF3): the Cinderella of the Cap‘n’Collar transcription factors

@article{Chevillard2011NFE2L3T,
  title={NFE2L3 (NRF3): the Cinderella of the Cap‘n’Collar transcription factors},
  author={Gr{\'e}gory Chevillard and Volker Blank},
  journal={Cellular and Molecular Life Sciences},
  year={2011},
  volume={68},
  pages={3337-3348}
}
NFE2L3 [Nuclear factor (erythroid-derived 2)-like 3] or NRF3, a member of the Cap‘n’Collar (CNC) family, is a basic-region leucine zipper (bZIP) transcription factor that was first identified over 10 years ago. Contrary to its extensively studied homolog NFE2L2 (NRF2), the regulation and function of the NFE2L3 protein have not yet attracted as much attention. Nevertheless, several recent reports have now shed light on the possible roles of NFE2L3. Structural and biochemical studies revealed a… CONTINUE READING
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