NFATc3 contributes to intermittent hypoxia-induced arterial remodeling in mice.

Abstract

Sleep apnea (SA) is defined as intermittent respiratory arrest during sleep and affects up to 20% of the adult population. SA is also associated with an increased incidence of hypertension and peripheral vascular disease. Exposing rodents to intermittent hypoxia during sleep mimics the cyclical hypoxia/normoxia of SA. We have previously shown that in mice… (More)
DOI: 10.1152/ajpheart.00341.2010

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