NFATc1 activates the acetylcholinesterase promoter in rat muscle.

Nuclear factor of activated T-cells (NFAT) plays a role in the response of muscle to chronic contractile activity that can result in fiber type switching and hypertrophy. These effects are due in part to activation of target genes following Ca2+-mediated nuclear translocation of NFAT. Acetylcholinesterase (AChE), a component of the neuromuscular junction… (More)