NFATC3-PLA2G15 Fusion Transcript Identified by RNA Sequencing Promotes Tumor Invasion and Proliferation in Colorectal Cancer Cell Lines.

@article{Jang2018NFATC3PLA2G15FT,
  title={NFATC3-PLA2G15 Fusion Transcript Identified by RNA Sequencing Promotes Tumor Invasion and Proliferation in Colorectal Cancer Cell Lines.},
  author={Jee-Eun Jang and Hwang-phill Kim and S. -M. Han and Hoon Jang and Si-Hyun Lee and Sang-Hyun Song and Duhee Bang and Tae-You Kim},
  journal={Cancer research and treatment : official journal of Korean Cancer Association},
  year={2018}
}
Purpose This study was designed to identify novel fusion transcripts (FTs) and their functional significance in colorectal cancer lines. Materials and Methods We performed paired-end RNA sequencing of 28 colorectal cancer (CRC) cell lines. FT candidates were identified using TopHat-fusion, ChimeraScan, and FusionMap tools and further experimental… CONTINUE READING