NF-kappaB regulatory mechanisms in alveolar macrophages from patients with acute respiratory distress syndrome.

@article{Moine2000NFkappaBRM,
  title={NF-kappaB regulatory mechanisms in alveolar macrophages from patients with acute respiratory distress syndrome.},
  author={P. Moine and R. Mcintyre and M. Schwartz and D. Kaneko and R. Shenkar and Y. le Tulzo and E. Moore and E. Abraham},
  journal={Shock},
  year={2000},
  volume={13 2},
  pages={
          85-91
        }
}
Activation of the nuclear regulatory factor NF-kappaB occurs in the lungs of patients with the acute respiratory distress syndrome (ARDS) and may contribute to the increased expression of immunoregulatory cytokines and other proinflammatory mediators in this setting. Because of the important role that NF-kappaB activation appears to play in the development of acute lung injury, we examined cytoplasmic and nuclear NF-kapppaB counterregulatory mechanisms, involving IkappaB proteins, in alveolar… Expand
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