NF-kappaB regulation in the immune system.

@article{Li2002NFkappaBRI,
  title={NF-kappaB regulation in the immune system.},
  author={Qiutang Li and Inder M Verma},
  journal={Nature reviews. Immunology},
  year={2002},
  volume={2 10},
  pages={
          725-34
        }
}
The nuclear factor-kappaB (NF-kappaB)/REL family of transcription factors has a central role in coordinating the expression of a wide variety of genes that control immune responses. There has been intense scientific activity in the NF-kappaB field owing to the involvement of these factors in the activation and regulation of key molecules that are associated with diseases ranging from inflammation to cancer. In this review, we focus on our current understanding of NF-kappaB regulation and its… CONTINUE READING

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