Corpus ID: 737315

NF-kappaB in transplantation: friend or foe?

@article{Tsoulfas2001NFkappaBIT,
  title={NF-kappaB in transplantation: friend or foe?},
  author={George Tsoulfas and David A. Geller},
  journal={Transplant infectious disease : an official journal of the Transplantation Society},
  year={2001},
  volume={3 4},
  pages={
          212-9
        }
}
  • George Tsoulfas, David A. Geller
  • Published in
    Transplant infectious disease…
    2001
  • Medicine
  • NF-kappaB is an inducible nuclear transcription factor regulating the expression of many genes. NF-kappaB activation may function as a master switch in a variety of immune and inflammatory processes, including sepsis and transplant tolerance. In this review, we summarize features of NF-kappaB regulation, as well as describe its role in intracellular signal transduction pathways. Subsequently, we concentrate on the role of NF-kappaB in the field of organ transplantation and the role of NF-kappaB… CONTINUE READING

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