NF-kappaB in renal inflammation.

@article{Sanz2010NFkappaBIR,
  title={NF-kappaB in renal inflammation.},
  author={A. Sanz and M. S{\'a}nchez-Ni{\~n}o and A. M. Ramos and J. Moreno and B. Santamaria and M. Ruiz-Ortega and J. Egido and A. Ortiz},
  journal={Journal of the American Society of Nephrology : JASN},
  year={2010},
  volume={21 8},
  pages={
          1254-62
        }
}
The NF-kappaB family of transcription factors regulates the induction and resolution of inflammation. Two main pathways, classical and alternative, control the nuclear translocation of NF-kappaB. Classical NF-kappaB activation is usually a rapid and transient response to a wide range of stimuli whose main effector is RelA/p50. The alternative NF-kappaB pathway is a more delayed response to a smaller range of stimuli resulting in DNA binding of RelB/p52 complexes. Additional complexity in this… Expand
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