NF-kappaB in lung cancer, a carcinogenesis mediator and a prevention and therapy target.

@article{Chen2011NFkappaBIL,
  title={NF-kappaB in lung cancer, a carcinogenesis mediator and a prevention and therapy target.},
  author={Wenshu Chen and Zi jian Li and Lang Bai and Yong Lin},
  journal={Frontiers in bioscience},
  year={2011},
  volume={16},
  pages={
          1172-85
        }
}
Lung cancer ranks as the first malignant tumor killer worldwide. Despite the knowledge that carcinogens from tobacco smoke and the environment constitute the main causes of lung cancer, the mechanisms for lung carcinogenesis are still elusive. Cancer development and progression depend on the balance between cell survival and death signals. Common cell survival signaling pathways are activated by carcinogens as well as by inflammatory cytokines, which contribute substantially to cancer… CONTINUE READING

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