NF-kappaB activation in peripheral blood monocytes/macrophages and T cells during acute Kawasaki disease.

@article{Ichiyama2001NFkappaBAI,
  title={NF-kappaB activation in peripheral blood monocytes/macrophages and T cells during acute Kawasaki disease.},
  author={T Ichiyama and T Yoshitomi and M Nishikawa and M Fujiwara and T Matsubara and T Hayashi and S Furukawa},
  journal={Clinical immunology},
  year={2001},
  volume={99 3},
  pages={373-7}
}
  • T Ichiyama, T Yoshitomi, +4 authors S Furukawa
  • Published 2001 in Clinical immunology
Kawasaki disease (KD) is a febrile disease of childhood characterized by systemic vasculitis, and the levels of many proinflammatory cytokines are elevated in the serum at the acute stage. We investigated the activation of transcription factor NF-kappaB for genes that encode the proinflammatory cytokines in CD14+ monocytes/macrophages and CD3+ T cells in peripheral blood by means of Western blot and flow cytometric analyses. Western blot analysis demonstrated that NF-kappaB activation was more… CONTINUE READING