NF-kappaB: a potential target for cancer chemoprevention and therapy.

@article{Sarkar2008NFkappaBAP,
  title={NF-kappaB: a potential target for cancer chemoprevention and therapy.},
  author={F. Sarkar and Y. Li},
  journal={Frontiers in bioscience : a journal and virtual library},
  year={2008},
  volume={13},
  pages={
          2950-9
        }
}
  • F. Sarkar, Y. Li
  • Published 2008
  • Medicine
  • Frontiers in bioscience : a journal and virtual library
Nuclear factor-kappaB pathway plays important roles in the control of cell proliferation, differentiation, apoptosis, inflammation, stress response, cell signaling transduction, and other physiological processes. Because the disorder of these physiological processes has been linked with the onset of cancers, NF-kappaB has been described as a major culprit in cancer. Experimental in vitro and in vivo studies have shown that down-regulation of NF-kappaB activity by natural and synthetic NF-kappaB… Expand
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