NF-kappa B2 is required for optimal CD40-induced IL-12 production but dispensable for Th1 cell Differentiation.

Abstract

NF-kappa B is a ubiquitously expressed transcription factor involved in the regulation of innate and adaptive immunity. As part of studies to define the role of various NF-kappa B family members in Th cell development and maintenance, we infected NF-kappa B2(-/-) and control mice with Leishmania major and followed disease progression. NF-kappa B2(-/-) mice… (More)

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