NF-kappa B is a central regulator of the intestinal epithelial cell innate immune response induced by infection with enteroinvasive bacteria.

@article{Elewaut1999NFkappaBI,
  title={NF-kappa B is a central regulator of the intestinal epithelial cell innate immune response induced by infection with enteroinvasive bacteria.},
  author={Dirk Elewaut and Joseph A. DiDonato and Jeong Min Kim and Franciose Truong and Lars Eckmann and Martin F. Kagnoff},
  journal={Journal of immunology},
  year={1999},
  volume={163 3},
  pages={1457-66}
}
Human intestinal epithelial cells up-regulate the expression of an inflammatory gene program in response to infection with a spectrum of different strains of enteroinvasive bacteria. The conserved nature of this program suggested that diverse signals, which are activated by enteroinvasive bacteria, can be integrated into a common signaling pathway that activates a set of proinflammatory genes in infected host cells. Human intestinal epithelial cell lines, HT-29, Caco-2, and T84, were infected… CONTINUE READING
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