NF-E2 disrupts chromatin structure at human beta-globin locus control region hypersensitive site 2 in vitro.

Abstract

The human beta-globin locus control region (LCR) is responsible for forming an active chromatin structure extending over the 100-kb locus, allowing expression of the beta-globin gene family. The LCR consists of four erythroid-cell-specific DNase I hypersensitive sites (HS1 to -4). DNase I hypersensitive sites are thought to represent nucleosome-free regions… (More)

Topics

Cite this paper

@article{Armstrong1996NFE2DC, title={NF-E2 disrupts chromatin structure at human beta-globin locus control region hypersensitive site 2 in vitro.}, author={Jennifer Alice Armstrong and Beverly M. Emerson}, journal={Molecular and cellular biology}, year={1996}, volume={16 10}, pages={5634-44} }