NF-κB in Cellular Senescence and Cancer Treatment

Abstract

The NF-κB pathway transcriptionally controls a large set of target genes that play important roles in cell survival, inflammation, and immune responses. While many studies showed anti-tumorigenic and pro-survival role of NF-κB in cancer cells, recent findings postulate that NF-κB participates in a senescence-associated cytokine response, thereby suggesting… (More)
DOI: 10.14348/molcells.2014.2353

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