NFκB signaling is important for growth of antiestrogen resistant breast cancer cells

Abstract

Resistance to endocrine therapy is a major clinical challenge in current treatment of estrogen receptor-positive breast cancer. The molecular mechanisms underlying resistance are yet not fully clarified. In this study, we investigated whether NFκB signaling is causally involved in antiestrogen resistant cell growth and a potential target for re-sensitizing… (More)
DOI: 10.1007/s10549-012-2053-1

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