NEW PERSPECTIVES ON ENDOCRINE SIGNALLING Tumour necrosis factor : a key regulator of adipose tissue mass


In addition to its established role in the immune system, tumour necrosis factor (TNF ) exerts complex regulatory actions on adipose tissue. TNF is produced in and secreted by the adipocyte and thus is in a position to exert a paracrine and/or autocrine role within adipose tissue. TNF affects many aspects of adipocyte function, from adipocyte development to… (More)


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