NEUTRALIZATION OF INFLUENZA VIRUS BY ANTIBODY: ATTACHMENT, UPTAKE AND UNCOATING OF NEUTRALIZED VIRUS IN CHICK EMBRYO CELLS

@inproceedings{Possee1981NEUTRALIZATIONOI,
  title={NEUTRALIZATION OF INFLUENZA VIRUS BY ANTIBODY: ATTACHMENT, UPTAKE AND UNCOATING OF NEUTRALIZED VIRUS IN CHICK EMBRYO CELLS},
  author={Robert D. Possee and Nigel J. Dimmock},
  year={1981}
}
We have investigated the attachment, uptake and uncoating by chick embryo fibroblast cell monolayers of an influenza type A virus neutralized to over 99.9% with heterogeneous rabbit antibody specific for the viral haemagglutinin. The rate of these processes was slightly slower than with non-neutralized virus but by 10 min. after inoculation there was no significant difference. We have thus demonstrated that neutralized virus is capable of undergoing a number of complex interactions with the… CONTINUE READING

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