• Medicine
  • Published 2006

NEUROSCIENCES AND NEUROANAESTHESIA Dexmedetomidine as an anaesthetic adjuvant in patients undergoing intracranial tumour surgery: a double-blind, randomized and placebo-controlled study †

@inproceedings{Tanskanen2006NEUROSCIENCESAN,
  title={NEUROSCIENCES AND NEUROANAESTHESIA Dexmedetomidine as an anaesthetic adjuvant in patients undergoing intracranial tumour surgery: a double-blind, randomized and placebo-controlled study †},
  author={P{\"a}ivi Tanskanen and J. Kytt{\"a} and Tarja Randell and Riku Aantaa},
  year={2006}
}
Background. Dexmedetomidine (DEX) has been shown to provide good perioperative haemodynamic stability with decreased intraoperative opioid requirements. It may have neural protective effects, and thus may be a suitable anaesthetic adjuvant to neurosurgical anaesthesia. Methods. Fifty-four patients scheduled for elective surgery of supratentorial brain tumour were randomized to receive in a double-blind manner a continuous DEX infusion (plasma target concentration 0.2 or 0.4 ng ml 1 ) or placebo… CONTINUE READING

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