NEUROBIOLOGY OF SCHIZOPHRENIA AND THE ROLE OF ATYPICAL ANTIPSYCHOTICS Prefrontal Neurons and the Genetics of Schizophrenia

@inproceedings{Weinberger2001NEUROBIOLOGYOS,
  title={NEUROBIOLOGY OF SCHIZOPHRENIA AND THE ROLE OF ATYPICAL ANTIPSYCHOTICS Prefrontal Neurons and the Genetics of Schizophrenia},
  author={Daniel R. Weinberger and Michael F. Egan and Alessandro Bertolino and Joseph H. Callicott and Venkata S. Mattay and Barbara K. Lipska and Karen Faith Berman and Terry E. Goldberg},
  year={2001}
}
This article reviews prefrontal cortical biology as it relates to pathophysiology and genetic risk for schizophrenia. Studies of prefrontal neurocognition and functional neuroimaging of prefrontal information processing consistently reveal abnormalities in patients with schizophrenia. Abnormalities of prefrontal information processing also are found in unaffected individuals who are genetically at risk for schizophrenia, suggesting that genetic polymorphisms affecting prefrontal function may be… CONTINUE READING