NEUROACTIVE STEROIDS

@article{Paul1993NEUROACTIVES,
  title={NEUROACTIVE STEROIDS},
  author={Steven M Paul},
  journal={Pediatric Research},
  year={1993},
  volume={33},
  pages={S9-S9}
}
  • S. Paul
  • Published 1 March 1992
  • Biology, Medicine, Chemistry
  • Pediatric Research
It is now well accepted that certain steroids rapidly alter the excitability of neurons via non-genomic mechanisms, resulting in behavioral effects within minutes following parenteral administration. Almost 50 years ago Selye first identified the sedative/anesthetic properties of pregnane and androstane steroids including the 3α-hydroxy A-ring reduced metabolites of progesterone and deoxycorticosterone, allopregnanolone and allotetrahydroDOC respectively. We have shown that these 3α-hydroxy A… 
Normal and Premature Adrenarche.
TLDR
This review highlights recent advances in molecular genetic and developmental biologic understanding of ZR development and insights into adrenarche emanating from mass spectrometric steroid assays.
Regulation of GABAA receptors by prolonged exposure to endogenous and exogenous ligands