NEUROACTIVE STEROIDS
@article{Paul1993NEUROACTIVES, title={NEUROACTIVE STEROIDS}, author={Steven M Paul}, journal={Pediatric Research}, year={1993}, volume={33}, pages={S9-S9} }
It is now well accepted that certain steroids rapidly alter the excitability of neurons via non-genomic mechanisms, resulting in behavioral effects within minutes following parenteral administration. Almost 50 years ago Selye first identified the sedative/anesthetic properties of pregnane and androstane steroids including the 3α-hydroxy A-ring reduced metabolites of progesterone and deoxycorticosterone, allopregnanolone and allotetrahydroDOC respectively. We have shown that these 3α-hydroxy A…
17 Citations
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