NEU4L sialidase overexpression promotes β-catenin signaling in neuroblastoma cells, enhancing stem-like malignant cell growth.

Abstract

Neuroblastoma (NB) is a frequently lethal tumor that occurs in childhood and originates from embryonic neural crest cells. The malignant and aggressive phenotype of NB is strictly related to the deregulation of pivotal pathways governing the proliferation/differentiation status of neural crest precursor cells, such as MYCN, Delta/Notch and Wnt/β-catenin… (More)
DOI: 10.1002/ijc.27450

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@article{Tringali2012NEU4LSO, title={NEU4L sialidase overexpression promotes β-catenin signaling in neuroblastoma cells, enhancing stem-like malignant cell growth.}, author={Cristina Tringali and Federica Cirillo and Giuseppe Lamorte and Nadia Papini and Luigi Anastasia and Barbara Lupo and Ilaria Proietti Silvestri and Guido Tettamanti and B Venerando}, journal={International journal of cancer}, year={2012}, volume={131 8}, pages={1768-78} }