NERP-2 regulates gastric acid secretion and gastric emptying via the orexin pathway.

@article{Namkoong2017NERP2RG,
  title={NERP-2 regulates gastric acid secretion and gastric emptying via the orexin pathway.},
  author={Cherl Namkoong and Koji Toshinai and T. M. Zaved Waise and Hideyuki Sakoda and Kazuki Sasaki and Yoichi Ueta and Min-Seon Kim and Naoto Minamino and Masamitsu Nakazato},
  journal={Biochemical and biophysical research communications},
  year={2017},
  volume={485 2},
  pages={409-413}
}
Neuroendocrine regulatory peptide (NERP)-2 is derived from a distinct region of VGF, a neurosecretory protein originally identified as a product of a nerve growth factor-responsive gene in rat PC12 cells. Colocalization of NERP-2 with orexin-A in the lateral hypothalamus increases orexin-A-induced feeding and energy expenditure in both rats and mice… CONTINUE READING