NDF/heregulin stimulates the phosphorylation of Her3/erbB3.

  title={NDF/heregulin stimulates the phosphorylation of Her3/erbB3.},
  author={Yukio Kita and J Barff and Yan Luo and Duanzhi Wen and David W. Brankow and Shengshou Hu and Ning Liu and Sally A. Prigent and William J. Gullick and M A Nicolson},
  journal={FEBS letters},
  volume={349 1},
Her3/erbB3 has been identified as a third member of the epidermal growth factor receptor (EGFR) family [(1989) Proc. Natl. Acad. Sci. USA 86, 9193-9197; (1990) Proc. Natl. Acad. Sci. USA 87, 4905-4909]. The natural ligand for Her3 has not been identified. Although recently NDF has been proposed as a specific ligand for Her4 [(1993) Nature 366, 473-475; (1993) J. Biol. Chem. 268, 18407-18410], we report here that Her3 was phosphorylated on tyrosine not only in three breast carcinoma cell lines… CONTINUE READING


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