NCL-CD10-270: a new monoclonal antibody recognizing CD10 in paraffin-embedded tissue.

  title={NCL-CD10-270: a new monoclonal antibody recognizing CD10 in paraffin-embedded tissue.},
  author={Gary G McIntosh and Anne Lodge and Peter Watson and Andrew G Hall and Kristi M Wood and John James Anderson and Brian Angus and Claydell H Horne and Ian Milton},
  journal={The American journal of pathology},
  volume={154 1},
CD10 (CALLA) antigen is expressed in a wide variety of epithelial and nonepithelial tissues, but its most significant application is in the diagnosis and classification of certain types of malignant lymphoma and leukemia. CD10 is expressed in a high percentage of cases of acute lymphoblastic leukemia (ALL), follicular lymphoma, Burkitt's lymphoma, and some hematopoietic tumors. Although the antigen is not lineage specific, CD10 expression is widely used to define subgroups within B-ALL and is a… CONTINUE READING
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