NCATS launches drug repurposing program

@article{Allison2012NCATSLD,
  title={NCATS launches drug repurposing program},
  author={Malorye Allison},
  journal={Nature Biotechnology},
  year={2012},
  volume={30},
  pages={571-572}
}
On May 17, Health Canada approved its first stem cell therapy, Prochymal, produced by Columbia, Maryland–based Osiris Therapeutics. Only a few weeks later, Medsafe, the medical regulatory agency in New Zealand, approved it, too. In both countries, the drug, a preparation of bone marrow–derived mesenchymal stem cells, will be used to treat graft-versus-host disease (GVHD), in children under 18. The approval is surprising given that in 2009, Prochymal missed two phase 3 trial endpoints in severe… CONTINUE READING

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