NCAM polypeptides in heart development: association with Z discs of forms that contain the muscle-specific domain

@article{Byeon1995NCAMPI,
  title={NCAM polypeptides in heart development: association with Z discs of forms that contain the muscle-specific domain},
  author={Mee Kyeong Byeon and Yukiko Sugi and Roger R. Markwald and S Valerie Hoffman},
  journal={The Journal of Cell Biology},
  year={1995},
  volume={128},
  pages={209 - 221}
}
Previous studies of neural cell adhesion molecule (NCAM) cDNAs have revealed an alternatively spliced set of small exons (12A, 12B, 12C, and 12D) that encode a region in the extracellular portion of the molecule known as the muscle-specific domain (MSD). The entire MSD region can be expressed in skeletal muscle, heart, and skin; only exons 12A and 12D have been found in brain. These studies did not reveal which NCAM polypeptides contain the MSD region or the immunohistochemical distribution of… CONTINUE READING

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