NATURE AND DISTRIBUTION ACCORDING TO AGE OF CUTANEOUS MANIFESTATIONS OF VITAMIN A DEFICIENCY: A STUDY OF TWO HUNDRED AND SEVEN CASES

@article{Frazier1936NATUREAD,
  title={NATURE AND DISTRIBUTION ACCORDING TO AGE OF CUTANEOUS MANIFESTATIONS OF VITAMIN A DEFICIENCY: A STUDY OF TWO HUNDRED AND SEVEN CASES},
  author={C. N. Frazier and Chuanyi Hu},
  journal={Archives of Dermatology},
  year={1936},
  volume={33},
  pages={825-852}
}
The classic manifestations of a deficiency of vitamin A in man, xerophthalmia and keratomalacia, have until recently been recognized as the only external lesions of this nutritional disorder. The failure of nutrition underlying such conditions is due either to an inadequate amount of the vitamin in the diet or to disease or functional derangements interfering with the utilization of this substance by the body. The relationship of the ocular changes to a deficiency of vitamin A has been… Expand
VARIATIONS IN THE CUTANEOUS MANIFESTATIONS OF VITAMIN A DEFICIENCY FROM INFANCY TO PUBERTY
In a former paper 1 dealing with the nature and age distribution of the cutaneous manifestations of vitamin A deficiency, it was pointed out that infants and children of prepubertal age did not oftenExpand
PIGMENTATION OF THE SKIN DUE TO VITAMIN A DEFICIENCY: REPORT OF A CASE AND REVIEW OF THE LITERATURE
Although the effects of vitamin A deficiency on the growth of the body and specifically on the eye have been recognized for more than twenty years, changes in the skin have been noted only within theExpand
THE PHARMACOLOGY AND THERAPEUTICS OF VITAMIN A
Treatment with vitamin A is indicated in disorders clearly due to deficiency of vitamin A in the diet. These disorders include nutritional night blindness, xerophthalmia, keratomalacia and a definiteExpand
Cutaneous Manifestations of Vitamin A Deficiency in Children.
TLDR
During the past eight months nine children were observed with cutaneous lesions of vitamin A deficiency similar to those described by Frazier and Hu in Chinese soldiers, by Loewenthal and Nicholls in prisoners in Africa and India respectively, and in various parts of the world by other observers. Expand
Cutaneous Manifestations in Rats with Advanced Vitamin A Deficiency *
TLDR
Specific‐pathogen‐free rats kept on a vitamin A‐deficient diet for approximately 5 months developed cutaneous alterations, especially in the periorbital and eyelid skin, which point to probable common mechanisms in the pathogenesis of these skin diseases. Expand
Use of vitamin C in acne vulgaris.
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  • Medicine
  • A.M.A. archives of dermatology and syphilology
  • 1954
TLDR
It is shown that, in some acne cases, lack of vitamin A causes a hyperkeratinization of the hair follicles, and an accumulation of this keratin, with the secretions of the glands, is a factor in the plugging of the pores. Expand
HISTOPATHOLOGY OF RAT SKIN IN AVITAMINOSIS A
TLDR
It is revealed that keratotic plugs may readily be induced in rats maintained on a diet deficient in vitamin A and that these plugs are identical with those occurring in the human subject. Expand
THE EELATION OF DEFICIENCIES OF VITAMIN A AND OF ESSENTIAL FATTY ACIDS TO FOLLICULAR HYPERKERATOSIS IN THE RAT. *
TLDR
Evidence is obtained to support the hypothesis of deflciency of vitamin A and a similar papular eruption of the skin to which Nicholls (1933) gave the name phrynoderma. Expand
Liver vitamin A in Darier's and Devergie's diseases.
  • T. Cornbleet
  • Medicine
  • The Journal of investigative dermatology
  • 1954
VITAMIN THERAPY IN DERMATOLOGY: WITH PARTICULAR REFERENCE TO VITAMIN D IN THE TREATMENT OF ACNE AND OF DISEASES DUE TO ALTERED USAGE OF CALCIUM
TLDR
This article stresses the results of my own clinical experience and statistical observations from my case records on the use of vitamin D mainly in the treatment of acne vulgaris, with a limited comparison with vitamin A. Expand
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During the winter and spring of 1928 and 1929 many cases of keratomalacia were seen in the hospital of the Peiping Union Medical College. Most of these occurred among Chinese soldiers, garrisoned inExpand
FOLLICULAR LESIONS IN VITAMIN A AND C DEFICIENCIES
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In the past year the authors have observed two cases of scurvy in adults in which follicular lesions were present and in one instance the resemblance of the lesions to those described in vitamin A deficiency was striking; in the other there were sufficient clinical and pathologic differences to justify the two processes. Expand
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A case of keratomalacia in an infant which terminated fatally and in which the microscopic examination showed extensive changes in many other organs of the body seems of especial interest. Expand
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The symptoms, pathology, course and complications of such deficiency diseases as pellagra, beriberi, and scurvy are well defined, even if the final details of their aetiologies have not been decided.Expand
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