SHOWING 1-8 OF 8 REFERENCES
Non‐enzymatic triggering of the ceramide signalling cascade by solar UVA radiation
- Biology, ChemistryThe EMBO journal
It is indicated that singlet oxygen triggers a third, non‐enzymatic mechanism of ceramide formation, which mediates solar ultraviolet (UV) A radiation‐induced expression of the intercellular adhesion molecule (ICAM)‐1.
Ectoin: An Effective Natural Substance to Prevent UVA-Induced Premature Photoaging
- Biology, MedicineSkin Pharmacology and Physiology
It was demonstrated that the UVA-induced second messenger release, transcription factor AP-2 activation, intercellular adhesion molecule-1 expression and mitochondrial DNA mutation could be prevented.
The multifunctional role of ectoine as a natural cell protectant.
- ChemistryClinics in dermatology
Genotoxicity of visible light (400-800 nm) and photoprotection assessment of ectoin, L-ergothioneine and mannitol and four sunscreens.
- BiologyJournal of photochemistry and photobiology. B, Biology
In vivo Assessment of Ectoin: A Randomized, Vehicle-Controlled Clinical Trial
- MedicineSkin Pharmacology and Physiology
Analytical evaluations according to the Wilcoxon rank-sum test indicate a general preference for the Ectoin treatment by the test subjects in both the application and the efficacy tests, clarifying that the natural cell protection concept of ECToin is transferable to skin care with manifold benefits.
Activation of transcription factor AP-2 mediates UVA radiation- and singlet oxygen-induced expression of the human intercellular adhesion molecule 1 gene.
- BiologyProceedings of the National Academy of Sciences of the United States of America
The capacity of UVA radiation and/or singlet oxygen to induce human gene expression through activation of AP-2 indicates a previously unrecognized role of this transcription factor in the mammalian stress response.
Senile hair graying: H2O2‐mediated oxidative stress affects human hair color by blunting methionine sulfoxide repair
- BiologyFASEB journal : official publication of the Federation of American Societies for Experimental Biology
It is shown for the first time by FT‐Raman spectroscopy in vivo that human gray/white scalp hair shafts accumulate hydrogen peroxide (H2O2) in millimolar concentrations and this new insight could open new strategies for intervention and reversal of the hair graying process.
Effects of Ectoine on follicular aging processes
- Henkel AG & Co KGaA,