NARINGIN AND RUTIN PREVENT D-GALACTOSAMINE-INDUCED HEPATIC INJURY IN RATS VIA ATTENUATION OF THE INFLAMMATORY CASCADE AND OXIDATIVE STRESS

@article{Mahmoud2013NARINGINAR,
  title={NARINGIN AND RUTIN PREVENT D-GALACTOSAMINE-INDUCED HEPATIC INJURY IN RATS VIA ATTENUATION OF THE INFLAMMATORY CASCADE AND OXIDATIVE STRESS},
  author={Mona F. Mahmoud and Dalia I. Hamdan and Michael Wink and Assem M. El-Shazly},
  journal={European Scientific Journal, ESJ},
  year={2013},
  volume={9}
}
The dried stems and leaves of Citrus jambhiri Lush. (Rutaceae) were extracted with aqueous methanol and the extracts were fractionated using light petroleum, chloroform and ethyl acetate. Column chromatography of the ethyl acetate fractions resulted in the isolation of naringin, rutin, hesperidin, and neohesperidin. Their structures were identified by MS and different NMR techniques. Liquid chromatography-electrospray ionization-mass spectrometry (LC-ESI-MS) of these fractions allowed the… 

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