NAR Breakthrough Article Promoter RNA links transcriptional regulation of inflammatory pathway genes

Abstract

Although many long non-coding RNAs (lncRNAs) have been discovered, their function and their association with RNAi factors in the nucleus have remained obscure. Here, we identify RNA transcripts that overlap the cyclooxygenase-2 (COX-2) promoter and contain two adjacent binding sites for an endogenous miRNA, miR-589. We find that miR-589 binds the promoter… (More)

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Cite this paper

@inproceedings{Matsui2013NARBA, title={NAR Breakthrough Article Promoter RNA links transcriptional regulation of inflammatory pathway genes}, author={Masayuki Matsui and Yongjun Chu and Huiying Zhang and Keith Gagnon and Sarfraz Shaikh and Satya N Kuchimanchi and Muthiah Manoharan and David R. Corey and Bethany A. Janowski}, year={2013} }