NAR Breakthrough Article Cycling of the E. coli lagging strand polymerase is triggered exclusively by the availability of a new primer at the replication fork

Abstract

Two models have been proposed for triggering release of the lagging strand polymerase at the replication fork, enabling cycling to the primer for the next Okazaki fragment—either collision with the 50-end of the preceding fragment (collision model) or synthesis of a new primer by primase (signaling model). Specific perturbation of lagging strand elongation… (More)

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Cite this paper

@inproceedings{Yuan2014NARBA, title={NAR Breakthrough Article Cycling of the E. coli lagging strand polymerase is triggered exclusively by the availability of a new primer at the replication fork}, author={Quan Yuan and Charles S McHenry}, year={2014} }