NANOGOLD decorated by pHLIP peptide: comparative force field study.

  title={NANOGOLD decorated by pHLIP peptide: comparative force field study.},
  author={Alexander Kyrychenko},
  journal={Physical chemistry chemical physics : PCCP},
  volume={17 19},
  • A. Kyrychenko
  • Published 2015
  • Chemistry, Medicine
  • Physical chemistry chemical physics : PCCP
The potential of gold nanoparticles (AuNPs) in therapeutic and diagnostic cancer applications is becoming increasingly recognized, which focuses on their efficient and specific delivery from passive accumulation in tumour tissue to directly targeting tumor-specific biomarkers. AuNPs functionalized by pH low insertion peptide (pHLIP) have recently revealed the capability of targeting acidic tissues and inserting into cell membranes. However, the structure of AuNP-pHLIP conjugates and fundamental… Expand
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