NADPH oxidases: new players in TNF-induced necrotic cell death.

@article{Berghe2007NADPHON,
  title={NADPH oxidases: new players in TNF-induced necrotic cell death.},
  author={Tom Vanden Berghe and Wim Declercq and Peter Vandenabeele},
  journal={Molecular cell},
  year={2007},
  volume={26 6},
  pages={
          769-71
        }
}
Necrosis is a caspase-independent cell death process involving the generation of reactive oxygen species (ROS). In a recent issue of Molecular Cell, Kim et al. (2007) reported on a novel TNF receptor 1 necrotic signaling complex inducing TRADD- and RIP1-dependent recruitment and activation of the ROS-generating Nox1 NADPH oxidase complex. 
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References

Publications referenced by this paper.
SHOWING 1-10 OF 10 REFERENCES

Mol

  • Kim, Y.-S., M. J. Morgan, S. Choki, Liu, Z.-G.
  • Cell 26, 675–687.
  • 2007
Highly Influential
7 Excerpts

Cell Death Differ

  • N. Festjens, T. Vanden Berghe, S. Cornelis, P. Vandenabeele
  • 14, 400–410.
  • 2007
Highly Influential
3 Excerpts

1Department of Pharmacology, University o *Correspondence: alexander.sorkin@uchsc DOI 10.1016/j.molcel.2007.06.003

  • Alexander Sorkin
  • 2007

demonst be ubiquitinated directly by E2igases

  • Cell, Hoeller
  • 2007

Biochim

  • N. Festjens, T. Vanden Berghe, P. Vandenabeele
  • Biophys. Acta 1757, 1371–1387.
  • 2006

FASEB J

  • L. Thon, H. Mohlig, +6 authors D. Adam
  • 19, –1956.
  • 2005
1 Excerpt

J

  • Y. Lin, S. Choksi, +6 authors Z. G. Liu
  • Biol. Chem. 279, 10822–10828.
  • 2004
3 Excerpts

Nat

  • J. D. Lambeth
  • Rev. Immunol. 4, 181–189.
  • 2004

EMBO J

  • S. Sakon, X. Xue, +8 authors H. Nakano
  • 22, 3898–3909.
  • 2003
1 Excerpt

Nat

  • N. Holler, R. Zaru, +7 authors J. Tschopp
  • Immunol. 1, 489–495.
  • 2000
2 Excerpts

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