NADPH oxidase p22phox and catalase gene variants are associated with biomarkers of oxidative stress and adverse outcomes in acute renal failure.

@article{Perianayagam2007NADPHOP,
  title={NADPH oxidase p22phox and catalase gene variants are associated with biomarkers of oxidative stress and adverse outcomes in acute renal failure.},
  author={Mary C. Perianayagam and Orfeas Liangos and Alexey Y. Kolyada and Ron Wald and Robert W MacKinnon and Lijun Li and Madhumathi Rao and Vaidyanathapuram S. Balakrishnan and Joseph V. Bonventre and Brian J.G. Pereira and Bertrand L. Jaber},
  journal={Journal of the American Society of Nephrology : JASN},
  year={2007},
  volume={18 1},
  pages={
          255-63
        }
}
Reactive oxygen species are important mediators of injury in acute renal failure (ARF). Although polymorphisms that affect key pro- and antioxidant enzymes might alter the susceptibility to oxidative stress-mediated injury, the use of genetic epidemiology for the study of oxidative stress-related genes has received little attention in ARF. The relationship of single-nucleotide polymorphisms in the coding region (C to T substitution at position +242) of the pro-oxidant enzyme NADPH oxidase… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 64 CITATIONS, ESTIMATED 48% COVERAGE

[Genetic determinants of acute renal damage risk and prognosis: a systematic review].

VIEW 5 EXCERPTS
CITES RESULTS & BACKGROUND
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2007
2018

CITATION STATISTICS

  • 3 Highly Influenced Citations