NADPH oxidase inhibitor, diphenyleneiodonium prevents necroptosis in HK-2 cells.

Abstract

The aim of the present study was to investigate the protective effect of the NADPH oxidase inhibitor, diphenyleneiodonium (DPI) against necroptosis in renal tubular epithelial cells. A necroptosis model of HK-2 cells was established using tumor necrosis factor-α, benzyloxycarbonyl-Val-Ala-Asp-fluoromethylketone and antimycin A (collectively termed TZA), as… (More)
DOI: 10.3892/br.2017.948

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Cite this paper

@article{Dong2017NADPHOI, title={NADPH oxidase inhibitor, diphenyleneiodonium prevents necroptosis in HK-2 cells.}, author={Wei Dong and Zhilian Li and Yuanhan Chen and Li Zhang and Zhiming Ye and Huaban Liang and Ruizhao Li and Lixia Xu and Bin Zhang and Shuangxin Liu and Weidong Wang and Chunling Li and Jialun Luo and Wei Shi and Xinling Liang}, journal={Biomedical reports}, year={2017}, volume={7 3}, pages={226-230} }